Project: Restoring endocannabinoid homeostasis to create the first effective & safe pharmacotherapy for PTSD

Acronym EndoCARE (Reference Number: 114985)
Duration 03/02/2021 - 03/08/2023
Project Topic EndoCARE aims to develop the first safe and effective pharmacotherapy for Post-Traumatic Stress Disorder (PTSD) based on our unique Selective Endocannabinoid Reuptake Inhibitor (SERI) SYT-510. With a novel mode of action (MoA), SYT-510 restores physiological endocannabinoid (ECx) levels. Here, we combine MoA research with efficacy studies in novel PTSD animal model and preclinical neuroimaging and biomarker discovery, enabling a translational preclinical package to derisk our clinical programme.
Network Eurostars 2
Call Eurostars Cut–off 14

Project partner

Number Name Role Country
1 Academic University Medical Center Amsterdam Partner Netherlands
2 Charles River Laboratories Den Bosch BV Partner Netherlands
3 Porsolt SAS Partner France
4 Pronexus Analytical AB Partner Sweden
5 Synendos Therapeutics AG Coordinator Switzerland