Project: Treatment enabled by REcombinant Advanced immunotherapy Technologies for HER2 positive tumours

Acronym TREAT-HER2 (Reference Number: 113775)
Duration 01/04/2020 - 01/04/2023
Project Topic We will develop a safe, effective and inexpensive vaccine for treatment of HER2+ cancers and prevention of recurrence. The vaccine combines state-to-the-art technologies in biotechnology and immunomodulation. Objectives are: 1) develop cGMP compatible vaccine manufacturing process; 2) delivery of safety, immunogenicity and efficacy data in (transgenic) mice, rabbits, nonhuman primates, and dogs developing spontaneously HER2+ carcinomas; 3) prepare for an IND/IMPD for a FIH study and partnering.
Network Eurostars 2
Call Eurostars Cut–off 12

Project partner

Number Name Role Country
1 LiteVax Partner Netherlands
2 AdaptVac Coordinator Denmark
3 Biomedical Primate Research Centre Partner Netherlands
4 ExpreS2ion Partner Denmark
5 University of Copenhagen Partner Denmark