JPIAMR-ACTION

Basic Information

Description

In the past 90 years since their discovery, antibiotics have saved millions of lives from bacterial diseases. However, emergingresistance to antimicrobials now threatens many advances achieved in modern medicine. AMR is a critical global health issue tightly linked with the One Health concept, which recognises that human and animal health are inextricably linked, and that diseasesare transmitted from humans to animals and vice versa. One Health also encompasses the environment as another link between humans and animals and a potential source and reservoir of AMR. Antimicrobial resistance is a growing global health concern and threatensthe future treatment and health of humans and animals. In addition, AMR limits our ability to achieve several of the UN Sustainable Development Goals (SDGs). The global challenge to address AMR goes beyond the production of new antibiotics and therapies. Reducingdemand for new antibiotics through public awareness, infection prevention and control, prudent and rational use of antibiotics for humans and animals, as well as effective diagnosis and surveillance of antibiotic-resistant infections and monitoring antibioticuse, are crucial when dealing with this problem globally. The transmission and spread of AMR in and between One Health compartments is complex, which emphasises the need for comprehensive interventions to reverse the trend of increasing human and animal infectionsresistant to treatment. The ERA-NET Cofund JPIAMR-ACTION will tackle this central challenge by supporting research and innovation for the development and testing of strategies and methodologies to reduce the transmission and spread of AMR within a full OneHealth spectrum. The JPIAMR-ACTION co-funded call and other activities will be instrumental in producing new innovative approaches, and advancing existing actions towards the development of new and improved interventions to inhibit or limit the developmentof AMR in humans, animals and the environment.

H2020 Societal Challenges

H2020-SC1 (Health, demographic change and wellbeing)