Project: The activity-driven ER-mitochondria Calcium Cycle (ERMCC) and protein misfolding in neurodegenerative diseases: finding targets for therapy

Neurodegenerative diseases like Amyotrophic Lateral sclerosis and Alzheimer’s disease occur mostly without identifyable cause, and are as yet uncurable. The project aims to develop a new strategy of neuroprotection by moderation of the endoplasmic-reticulum-mitochondria-calcium cycle (ERMCC) which links functional and structural metabolism in neurons and plays a central role in neuronal development and survival.

Duration 01/03/2009 - 29/02/2012
Network NEURON
Call NEURON-2008 Neurodegeneration

Project partner

Number Name Role Country
1 Friedrich-Schiller-University Jena Coordinator Germany
2 University of Goettingen Partner Germany
3 Fondazione S. Luca IRCCS Partner Italy
4 University of Valladolid Partner Spain