Project: Biocide Impact on Antimicrobial Resistance in Enterobacterales in One Health settings
| Acronym | BIORESIST (Reference Number: JPIAMR2024_IMPACT-132) |
| Duration | 01/04/2025 - 31/03/2028 |
| Project Topic | The abundant usage of antimicrobials in livestock in the past has allowed for farms to grow while keeping transmission of pathogens in check. As this resulted in the selection of antimicrobial resistance (AMR) to spread, many countries have now put restrictions on their usage, and aimed at disease prevention. Disinfection of stables and equipment using biocide chemicals has become a standard, but resistance to biocides also exist in bacterial communities. The abundant usage of biocides may be selecting for resistance against biocides to develop and be spread, similar as AMR-genes. Specifically, if biocide resistance occurs in multi-drug resistant bacteria, the usage of biocides contributes to the indirect selection of AMR. As part of National Action Plans against AMR, many countries are starting to monitor antimicrobial usage and AMR bacteria in the food chain. Specifically in the EU, monitoring is now mandatory and has been in place for several years at National Reference Laboratories (NRLs). As whole-genome sequencing (WGS) has become available, NRLs can use these data to investigate the prevalence of biocide resistance, and confirm an association with AMR. Furthermore, generating WGS data from their isolate collections can indicate changes over time. In developing nations, the usage of antimicrobials and biocides historically has been different. Comparisons will therefore be made of WGS data of collected isolates, but also of the usage of, and attitude towards antimicrobials and biocides in European countries and a low and middle income country in Africa. |
| Website | visit project website |
| Network | JPIAMR-ACTION |
| Call | 5TH JPIAMR-ACTION Joint Call 2024 |