Project: RNA modulation therapy for Huntington’s disease

Acronym ENCEPHALON (Reference Number: 12079)
Duration 01/03/2018
Project Topic ENCEPHALON aims to (1) advance the preclinical development of QRX-704, an innovative treatment for Huntington’s disease (HD), and (2) characterize the clinically relevant, non-toxic alternative Huntingtin protein isoform which is formed following treatment with QRX-704 using a multidisciplinary approach consisting of state-of-the-art methods. The results will provide in vitro and in vivo Proof of Concept, PK/PD and tolerability data to support further (pre)clinical development of QRX-704.
Network Eurostars 2
Call Eurostars Cut-Off 8

Project partner

Number Name Role Country
1 ProQR Therapeutics I B.V. Coordinator Netherlands
2 KTH Royal Institute of Technology Partner Sweden
3 University of Grenoble Alpes Partner France