Project: On-Axis 2-Photon Light-Sheet Generation for a 3-D in-vivo Imaging (Microscope) System

Acronym OASIS (Reference Number: 10266)
Duration 01/03/2016 - 01/03/2018
Project Topic We will build and characterize a novel, patent-pending 2-photon (2P) light-sheet microscope for minimally invasive sub-cellular imaging of live tissue. Its optical sectioning capabilities, large field-of-view, high speed and low photodamage are achieved by using spatially and temporally changing 2P excitation to create a light sheet. Fluorescence is confocally imaged through the same objective onto a fast camera. The concept will be validated by imaging brain astroglial Ca2+ signals.
Network Eurostars 2
Call Eurostars Cut-Off 4

Project partner

Number Name Role Country
23443 Centre National de la Recherche Scientifique (CNRS), Délégation Régionale Paris-Villejuif Partner France
23444 TILL I.D. GmbH Coordinator Germany