Project: Metrological characterisation of micro-vesicles from body fluids as non-invasive diagnostic biomarkers

Microvesicles are present in body fluids such as blood and urine and, because they are different in patients and healthy people, can be used as biomarkers for diseases such as cancer, diabetes and cardiovascular disease. The use of microvesicles as biomarkers would be less invasive than current techniques and could contribute to the earlier detection of common diseases and a reduction in the cost of healthcare. However, detecting microvesicles is difficult because of their small size and current techniques can only detect around 1–2 % of the total amount present, which is not accurate enough to make a diagnosis. This project will develop reliable, comparable and quantitative analysis of microvesicles. It will improve methods for collecting body fluids, isolating mircovesicles and measuring their size and total population.

Acronym HLT02 MetVes (Reference Number: HLT02)
Duration 01/06/2012 - 31/05/2015
Project Topic Metrology
Project Results
(after finalisation)
See Website
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Network EMRP
Call EMRP Call 2011 - Health, SI Broader Scope and New Technologies

Project partner

Number Name Role Country
1 VSL B.V. Coordinator Netherlands
2 Eidgenössisches Institut für Metrologie METAS Partner Switzerland
3 Physikalisch-Technische Bundesanstalt Partner Germany
4 Federale Overheidsdienst Economie, KMO, Middenstand en Energie Partner Belgium
5 Academisch Medisch Centrum bij de Universiteit van Amsterdam Observer Netherlands
6 AMC Medical Research B.V. Netherlands
7 Research Centre for Natural Sciences, Hungarian Academy of Sciences Hungary