Project: Providing the measurement infrastructure to allow quantitative diagnostic methods for biomarkers of coronary heart diseases

Acronym CardioMet (Reference Number: 18HLT10)
Duration 01/07/2019 - 30/06/2022
Project Topic Heart diseases are a major healthcare challenge in the EU. Cardiovascular disease, for instance, presents around 11 million new cases a year and is a factor in around 1.8 million deaths. Laboratory tests of certain biomarkers are used to guide treatments, but reliability is compromised by variation in results between tests, even for the same markers of disease. For example, the absence of agreed reference materials or procedures for cardiac troponin I (a marker for heart attacks) results in 85 % measurement variation between different test kits. However, traceable reference methods for the main biomarkers would substantially improve test performance and comparability. The project will characterise and develop measurement procedures to enable traceable quantification of relevant biomarkers with the support of the most significant standards making organisations. It will also develop a biosensor probe for faster diagnosis of heart attacks, and promote the methods developed to laboratories, medical device makers, and medical associations. Reliable quantification of cardiac markers will reduce the risk of incorrect diagnoses, reduce the chance of patient deaths and help lower healthcare costs.
Website visit project website
Network EMPIR
Call EMPIR Call 2018

Project partner

Number Name Role Country
1 Physikalisch-Technische Bundesanstalt Coordinator Germany
2 Bundesanstalt fuer Materialforschung und -pruefung Partner Germany
3 LGC Limited Partner United Kingdom
4 Laboratoire national de métrologie et d'essais Partner France
5 Turkiye Bilimsel ve Teknolojik Arastirma Kurumu Partner Turkey
6 Assistance publique – Hôpitaux de Paris Partner France
7 Greater Glasgow Health Board Partner United Kingdom
8 Johann Wolfgang Goethe Universität Frankfurt am Main Partner Germany
9 Inst Cardiometabolisme Nutrition ICAN Partner France
10 Academisch Ziekenhuis Leiden Partner Netherlands
11 Stiftung für Pathobiochemie und Molekulare Diagnostik Partner Germany
12 Uppsala Universitet Partner Sweden