Project: Metrology to enable rapid and accurate clinical measurements in acute management of sepsis

Acronym SEPTIMET (Reference Number: 18HLT03)
Duration 01/09/2019 - 31/08/2022
Project Topic Sepsis is a life-threatening complication of infections, responsible for about 700,000 deaths a year in Europe, and six million worldwide. To improve the speed and accuracy of sepsis diagnoses using existing in vitro diagnostic (IVD) methods, measurements of established biomarkers for this condition need to be traceable and techniques compliant with EU regulations. Newly developed techniques also require metrological evaluation, as well as the machine learning algorithms used to identify solutions for sepsis management. This project will improve the accuracy and speed of methods used to diagnose sepsis and its causes, by developing traceable procedures and reference materials for currently used biomarkers, plus new techniques will be assessed. Methods developed in the project will enable IVD manufacturers to demonstrate the accuracy of their technologies for reliable clinical use, including near-patient tests for diagnostics at the point of care. The project will contribute to standards development, with the ultimate objective of faster, more accurate sepsis diagnosis for improved patient survival rates.
Website visit project website
Network EMPIR
Call EMPIR Call 2018

Project partner

Number Name Role Country
1 LGC Limited Coordinator United Kingdom
2 Laboratoire national de métrologie et d'essais Partner France
3 Eidgenössisches Institut für Metrologie METAS Partner Switzerland
4 Nacionalni Institut za Biologijo Partner Slovenia
5 NPL Management Limited Partner United Kingdom
6 Physikalisch-Technische Bundesanstalt Partner Germany
7 Assistance publique – Hôpitaux de Paris Partner France
8 Ben-Gurion University of the Negev Partner Israel
9 Commissariat à l'énergie atomique et aux énergies alternatives Partner France
10 Great Ormond Street Hospital for Children National Health Service Trust Partner United Kingdom
11 Warszawski Uniwersytet Medyczny Partner Poland
12 Royal Surrey County Hospital NHS Foundation Trust Partner United Kingdom