Project: Metrology for clinical implementation of dosimetry in molecular radiotherapy

The use of radiopharmaceuticals for treating cancer in Europe has grown considerably over the last few years. Current practice is to administer a carefully measured radioactivity dose to a patient, without taking into account the amount of radioactivity actually absorbed by tissue in the patient’s body. As a result, the administered dose is not the best indicator of effective treatment, and accurate knowledge of the radioactivity absorbed by tissue would make a significant difference to the success of many patients’ treatments. A recent EU Directive (2013/59/EURATOM) will require individual dose planning based on absorbed dose measurements for patients from February 2018. However, the planning process is complex and no standard methods exist to support clinics’ compliance with the regulation. This project will overcome these obstacles by building on the work of previous EMRP project HLT11 MetroMRT, developing a robust measurement protocol and providing standardised methods, test objects and resources to support molecular radiotherapy clinics in setting up and validating dosimetry, thereby improving patient outcomes.

Acronym 15HLT06 MRTDosimetry (Reference Number: 15HLT06)
Duration 01/06/2016 - 01/06/2019
Project Topic Metrology
Project Results
(after finalisation)
See Website
Website visit project website
Network EMPIR
Call EMPIR CALL 2015

Project partner

Number Name Role Country
1 NPL Management Limited Coordinator United Kingdom
2 Physikalisch-Technischer Pruefdienst des Bundesamt fuer Eich- und Vermessungswesen Partner Austria
3 Commissariat à l'énergie atomique et aux énergies alternatives Partner France
4 Cesky Metrologicky Institut Partner Czech Republic
5 Agenzia Nazionale per le nuove tecnologie, l’energia e lo sviluppo economico sostenibile Partner Italy
6 Studiecentrum voor Kernenergie, Centre d'Etude de l'Energie Nucléaire, Fondation d’Utilité Publique Partner Belgium
7 Arcispedale Santa Maria Nuova Azienda Ospedaliera Partner Italy
8 The Christie NHS Foundation Trust Partner United Kingdom
9 Institut National de la Sante et de la Recherche Medicale (INSERM) Partner France
10 Lunds Universitet Partner Sweden
11 "Theagenio" Anticancer Hospital of Thessaloniki Partner Greece
12 Universitätsklinikum Würzburg - Klinikum der bayerischen Julius - Maximilians - Universität Partner Germany
13 Azienda Ospedaliero Universitaria Policlinico S. Orsola Malpighi Observer Italy
14 Idryma Iatroviologikon Ereunon Akademias Athinon Observer Greece
15 Cardiff University Observer United Kingdom
16 Ospedale Pediatrico Bambino Gesù Observer Italy
17 Oxford University Hospitals NHS Foundation Trust Observer United Kingdom
18 Royal Surrey County Hospital NHS Foundation Trust Observer United Kingdom