Paediatric drug formulations for poverty-related diseases 2019

Basic Information

Poverty-related diseases (PRDs) remain the leading causes of morbidity and mortality in sub-Saharan Africa, especially during childhood. Despite progress in other age groups, effective treatment and prevention of PRDs in paediatric populations is often lacking and/or lagging. The frequent exclusion of children and adolescents from clinical trials and the paucity of available products that target this group are factors that contribute to this population having one of the lowest health indicators. Additional challenges relate to the limited financial incentives associated with the adaption of off-patent medicines to the specific needs of paediatric populations. Therefore, concerted efforts are needed to increase access to potentially life-saving, cost-effective interventions to prevent and treat PRDs in children and to enhance the use of existing interventions in this population.

Network EDCTP2
Aim of the joint call Proposals should focus on the adaptation of existing medicinal products (drugs), including off-patent products, to the specific needs of children (0-17 years of age). Proposals may address any of the PRDs within the remit of the EDCTP2 programme. Proposals should include one (or more) clinical trials conducted in sub-Saharan Africa to assess the safety, efficacy and pharmacokinetics of the drug(s), and/or the development of age-appropriate formulations. Projects must assure that the clinical trials are conducted appropriately, in line with guidelines on pharmaceutical development of medicines for paediatric use*, respecting current legislation and considering the ethical aspects and particular needs of the study subjects and their families. Applicants should seek advice on the clinical trial design from the appropriate regulatory agency(ies) before developing the application.
Type of joint call One Stage - Call with no pre-proposals submission
Launch date 10/06/2019
Deadline Full-Proposal 10/10/2019 Submitted proposal: n/a
Evaluation End Date n/a Successful proposal: n/a Proposals funded: n/a
Is call co-funded? No
Call follow up funding n/a
Call reasons n/a
Research fields
  • Health
Type of research n/a
Target groups n/a
Participating networks n/a

Organisations Participating

No participating organisations found.