Project: Treating cancer by targeting endogenous retroviral fossils encoded within the human genome.

Acronym TREATCANCERV (Reference Number: 113556)
Duration 01/01/2020 - 03/01/2023
Project Topic We want to translate broad and curative anticancer efficacy against murine endogenous retrovirus (ERVs) envelope (Env) and particle genes, into treatments against human ERV (HERVs) expressing cancers. The deliverable will be human ex vivo and murine in vivo validated novel Virus-Like-Vaccine (VLV) candidates and monoclonal antibodies capable of blocking the immunosuppressive domain of cancer expressed ERV Envs. These candidates will be ready for clinical development (GMP/TOX) after the project.
Network Eurostars 2
Call Eurostars Cut–off 11

Project partner

Number Name Role Country
1 InProTher Aps Coordinator Denmark
2 Sirion Biotech GmbH Partner Germany
3 Københavns Universitet Partner Denmark
4 Universität Regensburg Partner Germany