Project: A novel multifactorial biomarker-based Companion Predictive Model for hypoxia-activated prodrugs.

Acronym COMPACT! (Reference Number: 12053)
Duration 01/05/2018
Project Topic COMPACT will result in a validated spatially resolved multifactorial Biomarkers-based Companion Predictive Model (B-CPM) for hypoxia-activated prodrugs (HAPs)(Fig1,2). This will be done by integrating and validating distinct HAP-related biomarkers for: hypoxia, activity of nitroreductases, cellular sensitivity, and pharmacokinetic HAP features. COMPACT’s B-CMP will advance HAP clinical development and enable patient stratification in clinics. Watch
Network Eurostars 2
Call Eurostars Cut-Off 8

Project partner

Number Name Role Country
1 Convert Pharmaceuticals SA Coordinator Belgium
2 Maastricht University Partner Netherlands