Project: A novel multifactorial biomarker-based Companion Predictive Model for hypoxia-activated prodrugs.

Acronym	COMPACT! (Reference Number: 12053)
Duration	01/05/2018
Project Topic	COMPACT will result in a validated spatially resolved multifactorial Biomarkers-based Companion Predictive Model (B-CPM) for hypoxia-activated prodrugs (HAPs)(Fig1,2). This will be done by integrating and validating distinct HAP-related biomarkers for: hypoxia, activity of nitroreductases, cellular sensitivity, and pharmacokinetic HAP features. COMPACT’s B-CMP will advance HAP clinical development and enable patient stratification in clinics. Watch https://youtu.be/g65d6PxPzyE.
Network	Eurostars 2
Call	Eurostars Cut-Off 8

Project partner

Number	Name	Role	Country
1	Convert Pharmaceuticals SA	Coordinator	Belgium
2	Maastricht University	Partner	Netherlands