Project: HepaPlateTM – High throughput Organ-on-a-Chip model for Liver Toxicity Screening

We will develop an Organ-on-a-Chip hepatotoxicity-screening platform for toxicological evaluation of small molecules (Annex A). This innovative, high throughput approach combines Medicyte’s unlimited source of upcyte® Cells and MIMETAS OrganoPlates™ (Annex C). The liver model will consist of 3D hepatocyte organoids with sinusoidal endothelial and immune cells (Annex B). The HepaPlate™ will be validated for a compound library with known hepatotoxicity profiles.

Acronym HepaPlateTM (Reference Number: 9804)
Duration 01/09/2015 - 01/09/2017
Project Topic Biological Sciences / Technologies
Network Eurostars 2
Call Eurostars Cut-Off 3

Project partner

Number Name Role Country
21845 MIMETAS Coordinator Netherlands
21846 Medicyte GmbH Partner Germany