Project: A novel in vitro organ-on-a-chip heart failure model for drug development.
| Acronym | HeartCHIP (Reference Number: 10131) |
| Duration | 01/05/2016 - 01/05/2019 |
| Project Topic | HeartCHIP will develop a novel in vitro heart failure (HF) model for preclinical drug discovery and efficacy testing based on high content microfluidic Organ-on-Chip (OOC) technology. Prevalent genetic mutations will be introduced with gene editing CRISPR/CAS9 system in human induced pluripotent stem cells, which will be differentiated into cardiomyocytes. Integration of non-destructive functional microscopy and detection biomarkers will ensure a high-content platform for drug efficacy screening |
| Network | Eurostars 2 |
| Call | Eurostars Cut-Off 4 |
Project partner
| Number | Name | Role | Country |
|---|---|---|---|
| 22985 | Pluriomics B.V. | Coordinator | Netherlands |
| 22986 | Erasmus Universitair Medisch Centrum Rotterdam | Partner | Netherlands |
| 22987 | Ibidi GmbH | Partner | Germany |