Project: A novel in vitro organ-on-a-chip heart failure model for drug development.

Acronym HeartCHIP (Reference Number: 10131)
Duration 01/05/2016 - 01/05/2019
Project Topic HeartCHIP will develop a novel in vitro heart failure (HF) model for preclinical drug discovery and efficacy testing based on high content microfluidic Organ-on-Chip (OOC) technology. Prevalent genetic mutations will be introduced with gene editing CRISPR/CAS9 system in human induced pluripotent stem cells, which will be differentiated into cardiomyocytes. Integration of non-destructive functional microscopy and detection biomarkers will ensure a high-content platform for drug efficacy screening
Network Eurostars 2
Call Eurostars Cut-Off 4

Project partner

Number Name Role Country
22985 Pluriomics B.V. Coordinator Netherlands
22986 Erasmus Universitair Medisch Centrum Rotterdam Partner Netherlands
22987 Ibidi GmbH Partner Germany