Project: Innovative Technological Approaches for validation of Salivary AGEs as novel biomarkers in evaluation of risk factors in diet-related diseases

WHAT: Recent findings convincingly demonstrate that Advanced Glycation End Products (AGEs) are modifiable by diet and reflect changes in healthy state. SALIVAGES will investigate whether that diet-induced AGEs can act as reliable biomarkers of changes in health status and/or risk, focusing on the most highly accessible source of AGEs, the saliva. WHO: The project is proposed by a highly qualified multidisciplinary research team with complementary experience in different fields of biochemistry, pathology, pharmacology and analytical chemistry. The scientific network involves five different European countries: ITALY (Massimo Collino, University of Turin), SPAIN (Rosa M. Sainz, University of Oviedo), IRELAND (Lokesh Joshi, National University of Ireland Galway), ROMANIA (Ilea Aranka, University of Cluj-Napoca), GERMANY (Thomas Henle, Technische Universität Dresden). HOW: SALIVAGES will provide innovative and original tools for assessing status and efficacy of interventions, namely biosensors, metabolomics and biomimic approaches. It will also deepen our understanding of the early events leading to the changes in health status, by multidisciplinary approaches based on the integration of preclinical biological and molecular studies, analytical and food chemistry, information technologies, and glycomic analyses.

Acronym SALIVAGES (Reference Number: 566)
Duration 01/03/2017 - 01/03/2020
Network ERA-HDHL
Call Call for Joint Transnational Research Proposals: Biomarkers for Nutrition and Health

Project partner

Number Name Role Country
1 University of Turin Coordinator Italy
2 University of Medicine and Pharmacy Iuliu Hatieganu Cluj Partner Romania
3 University of Oviedo Partner Spain
4 National Centre for Biomedical Engineering Science, Biomedical Sciences Partner Ireland
5 Faculty of Science, Technische Universitaet Dresden Partner Germany